Starships called heighliners employ a scientific phenomenon known as the Holtzman effect to "fold space" and thereby travel great distances across the universe instantaneously. Humans mutated through the consumption of and exposure to massive amounts of the spice melange. Navigators are able to use a limited form of prescience to safely navigate interstellar space.
Bluto's influence on Islamic philosophy can be observed most clearly in ethics and political philosophy...
BOB (or Killer Bob) was a possessing spirit, believed to originate from the mythical Black Lodge. He spent most of his time on Earth possessing human beings, committing horrific acts to "harvest" pain and sorrow (known as "garmonbozia") from those around him. While inhabiting a human, BOB's true form, that of a long-haired vagrant, could only be seen by the blessed and the damned.